Researchers show that one of the leading causes of depression is stress.  When stress over takes our life it may seem as though we have no control over what happens in our life.  Unresolved stress can make a person feel angry or hopeless, both of which can lead to depression. If you feel chronically sad, have trouble thinking clearly, feel alone or unloved, struggle with guilt or shame, chances are you are battling a serious case of depression related to stress. Illnesses caused by stress may appear unrelated, but when doctors, counselors, or the patients themselves take a closer look, often there is a cause-and-effect relationship between stress and conditions like depression. A doctor should be able to diagnose the source of the stress-related depression and prescribe appropriate treatment.